Conventional Aortic Valve Replacement in Patients over 70 Years of Age: Outcomes and Quality of Life

Mariam M. Nersisyan, Irina E. Olofinskaya, Yulia V. Goncharuk, Renat M. Muratov , Ivan I. Skopin, Leo A. Bockeria

A.N. Bakoulev Scientific Center for Cardiovascular Surgery, Moscow, Russia

Date, time and location: 2018.05.25 13:30, Exhibition area, 1st Floor. Zone – D

Abstract

Objective. The aim of this study was to evaluate results and quality of life in patients over 70 years after on-pump aortic valve replacement (AVR).

Material and methods. We included 125 patientswho underwent aortic valve replacement due to aortic valve stenosis, alone or in combination with another procedure. The mean age was75,6 ± 2,67.Patients have been divided into groups of 70-79 years old and over 80. Functional class by NYHA was3,2 ± 0,7 preoperatively. The medical outcomes study SF-36 and Minnesota Living with Heart Failure Questionnaire were completed preoperatively and after surgery. The mean follow-up time was 24 ±3,2 months.

Results.Hospital mortality was 6,4%. Early postoperative complications were observed in 25,6% cases: cardiac failure (11.2%), respiratory insufficiency (13.6%), atrial fibrillation or flutter (9,6%), cerebrovascular disorders(9,6%), stroke(4%), renal failure( 6,4%). The analysis on patients over 80 years was performed with no statistical difference from the entire group. During the follow time one patient died 4 months after surgery. Positive changes of basic hemodynamic parameters were observed in the early postoperative period and persisted during the follow up in majority of patients 70-79 years old and in the group over 80 years. Survived patients showed statistically significant changes in the mean values of NYHA functional class (1.7±0.5) as well as higher scores on the MOS SF-36 and improved MLHFQ results after surgery.

Conclusion.The results demonstratedsignificant improvement of clinical and functional state in patients 70-79 and over 80 years old during the follow up period. Quality of life assessed with the MOS SF-36 andMLHFQ revealed evident improvement and demonstrated good surgical treatment results.