Immediate and Long-term Results of Percutaneous Coronary Interventions in Patients with Ischemic Heart Disease and Concomitant Oncopathology
- #CI/INT 01-EP-6
- Cardiology and Imaging in Cardiac Surgery/Intraoperative and Early Assessment of the Results of Surgery. E-POSTER (ORAL) SESSION
- E-Poster (oral)
Immediate and Long-term Results of Percutaneous Coronary Interventions in Patients with Ischemic Heart Disease and Concomitant Oncopathology
Mikhail M. Dombrovskiy 1, Tatyana G. Nikitina 1, Karen V. Petrosyan 1, Bagrat G. Alekyan 2, Leo A. Boskeria 1
1 A.N. Bakulev National Medical Research Center of Cardiovascular Surgery of Ministry of Health of the Russian Federation, Moscow, Russia; 2 Institute of Surgery A.V. Vishnevsky of Ministry of Health of the Russian Federation. Str. Most of Serpukhov, 27, Moscow, 115478, Russian Federation, Moscow , Russia;
Date, time and location: 2018.05.26 17:00, Exhibition area, 1st Floor. Zone – A
Abstract
Material and methods. From 2008 to 2017, 47 patients with IHD and oncopathology were examined and treated in our center. Patients underwent PCI in the first stage. Stents without drug coating were implanted in 27 (57.4%) patients, with drug coating - 20 (42.6%) patients. At discharge, continuous double antiplatelet therapy (DAPT) was recommended for at least 1 month with implantation of stents without drug coverage and 3 months for implantation of coated stents. Treatment of oncology was carried out on average 2.5 ± 3 months after PCI, surgical treatment was performed 24 (51.1%) patients, chemotherapy / radiation therapy - 19 (40.4%) and combined treatment - 4 (8.5%).
In surgical treatment of oncopathology, patients were recommended to stop DAPT and switch to heparin 5-7 days before the intervention of 26 (92.9%), and 2 (7.1%) - to perform treatment against acetylsalicylic acid. Return to DAPT (acetylsalicylic acid + clopidogrel) was recommended within the first 6-48 hours after the operation.
Results: none of the patients showed significant intraoperative blood loss, as well as acute violations of coronary blood supply during the treatment of oncopathology. Angina recurrence was noted in 4 (8.5%) patients in time to one year after PCI and 2 (4.3%) patients later. All fatal outcomes in 9 (19.1%) patients during 5 years of follow-up (mean follow-up period - 20.7 ± 15) were due to the progression of oncology.
Conclusions:it is possible to successfully carry out two-stage treatment in patients with IHD and oncology, where the first stage was PCI. Strict adherence to DAPT is necessary within the recommended time frame.