Results of Arterial Switch Operation for Transposition of the Great Arteries with Mild Left Ventricular Outflow Tract Obstruction


  • #CH/NEW 01-O-8
  • Congenital Heart Surgery/Newborn Critical Congenital Cardiac. SESSION-1
  • Oral

Results of Arterial Switch Operation for Transposition of the Great Arteries with Mild Left Ventricular Outflow Tract Obstruction

Qin Yan, Jing hao Zheng, Hai bo Zhang, Jin fen Liu, Zhi wei Xu

Shanghai Childens Medical Center, Shanghai, China

Date, time and location: 2018.05.26 08:30, Press Hall, 2F

Abstract

ObjectiveTo study retrospectively the results of arterial switch operation (ASO) for transposition of the great arteries (TGA) with mild left ventricular outflow tract obstruction (LVOTO)

Methods Between Jan 2000 and Dec 2015, 38 patients with TGA and anatomic LVOTO underwent ASO. 17 patients had a ventricular septal defect. Median follow-up was 6.8 ± 2.5 years. Univariate and multivariate risk analyses for late LVOTO, aortic regurgitation and LVOT reintervention were performed.

Results Overall in-hospital survival was 100%. No death at the follow-up. 7 (18%) had mild to moderate aortic regurgitation. Actuarial freedom from LVOTO was 90% ± 5% at 5 years. The mean LVOT peak gradient was 17± 5 mm Hg at the latest follow-up. Freedom from reinterventions of LVOTO was 93% at 5 years.The LVOT gradient and the presence of ventricular septal defect or a bicuspid valve do not influence outcomes.

Conclusions ASO for TGA with mild LVOTOseem to offer favorable intermediate survival.It would be better option to do ASO forTGA/mild LVOTO patients with reasonable valvular or subvalvular LVOTO, or both.


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